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Product > Antibody > ABL2 Monoclonal Antibody
ABL2 Monoclonal Antibody
ABL2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1H1B11
Host: Mouse
Reactivity:Human
Applications: ICC
Product Summary
Size:
50μL
Clonality: 1H1B11
Host: Mouse
Reactivity: Human
Applications: ICC
Product overview
Code
BT-MCA2478
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1H1B11
Immunogen
Purified recombinant fragment of ABL2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.
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