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Product > Antibody > HER-2 Monoclonal Antibody
HER-2 Monoclonal Antibody
HER-2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 9B9D8
Host: Mouse
Reactivity:Human
Applications: IHC
Product Summary
Size:
50μL
Clonality: 9B9D8
Host: Mouse
Reactivity: Human
Applications: IHC
Product overview
Code
BT-MCA4242
Host
Mouse
Isotype
Mouse IgG2b
Size
50μL
Clonality
9B9D8
Immunogen
Purified recombinant fragment of HER-2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis
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