Trim5a Monoclonal Antibody

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Home > Product > Antibody > Trim5a Monoclonal Antibody

Trim5a Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB,IHC

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB,IHC

Product overview

Code

BT-MCA4213

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human trim5 alpha expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

Uniprot accession

Q9C035:;

Gene ID

85363

Synonyms

RNF88;TRIM5alpha

Research area

Others

Target protein

Trim5a

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
ELISA	1:10000

Images

Western blot analysis using Trim5a mouse mAb against human breast carcinoma tissue lysate.

Immunohistochemical analysis of paraffin-embedded human metastatic adenocarcinoma(A) and stomach adenocarcinoma (B), showing cytoplasmic localization using Trim5a mouse mAb with AEC staining (A) and DAB staining(B).

Western blot analysis using Trim5a mouse monoclonal antiobdy against truncated Trim5a recombinant protein.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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