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Product > Antibody > EphB6 Monoclonal Antibody
EphB6 Monoclonal Antibody
EphB6 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 8E7H12
Host: Mouse
Reactivity:Human
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 8E7H12
Host: Mouse
Reactivity: Human
Applications: WB,IHC
Product overview
Code
BT-MCA3440
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
8E7H12
Immunogen
Purified recombinant fragment of EphB6 expressed in E. Coli.
Formulation
Purified antibody in PBS containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
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