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Product > Antibody > APP Monoclonal Antibody
APP Monoclonal Antibody
APP Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1B11F3
Host: Mouse
Reactivity:Human
Applications: IHC
Product Summary
Size:
50μL
Clonality: 1B11F3
Host: Mouse
Reactivity: Human
Applications: IHC
Product overview
Code
BT-MCA3013
Host
Mouse
Isotype
Mouse IgG2a
Size
50μL
Clonality
1B11F3
Immunogen
Purified recombinant fragment of APP expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Amyloid precursor protein(APP) ,with 32-amino acid protein (about 35 kDa), is part of a super-family of transmembrane and secreted proteins. It appears to have a number of roles, including regulation of haemostasis and mediation of neuroprotection. APP undergoes alternative splicing, resulting in several isoforms . Proteolytic cleavage of amyloid precursor protein leads to the formation of the 4 kDa amyloid beta/A4 protein, which is present in human platelets. APP is also involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients.
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