MSH6 Monoclonal Antibody

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Home > Product > Antibody > MSH6 Monoclonal Antibody

MSH6 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA4844

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human MSH6 (AA: 217-395) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants.

Uniprot accession

Q13509:;

Molecular weight

50kDa

Gene ID

10381

Synonyms

CDCBM;CDCBM1;CFEOM3;CFEOM3A;FEOM3;TUBB4;beta-4

Research area

Others

Target protein

MSH6

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using TUBB3 mouse mAb against NIH/3T3 (1), Hela (2), and A549 (3) cell lysate.

Flow cytometric analysis of Hela cells using TUBB3 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using TUBB3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded cerebellum tissues using TUBB3 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$180.00
50μL

$120.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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