MRE11 Monoclonal Antibody

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Home > Product > Antibody > MRE11 Monoclonal Antibody

MRE11 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Monkey, Rat

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Monkey,Rat

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA4568

Host

Mouse

Isotype

Mouse IgG2b

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human MRE11 (AA: 182-582) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Uniprot accession

P49959:;

Molecular weight

80.6kDa

Gene ID

4361

Synonyms

ATLD;HNGS1;MRE11A;MRE11B

Research area

Others

Target protein

MRE11

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using MRE11 mouse mAb against Hela (1), A431 (2), MCF-7 (3), Jurkat (4), HepG2 (5), K562 (6), COS-7 (7), PC-12 (8) and NIH/3T3 (9) cell lysate.

Flow cytometric analysis of Hela cells using MRE11 mouse mAb (green) and negative control (red).

Flow cytometric analysis of K562 cells using MRE11 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using MRE11 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using MRE11 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded Mouse testis tissues using MRE11 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded Rat testis tissues using MRE11 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded Rabbit testis tissues using MRE11 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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