TNFRSF11A Monoclonal Antibody

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Home > Product > Antibody > TNFRSF11A Monoclonal Antibody

TNFRSF11A Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat

Applications: WB,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat

Applications: WB,FCM

Product overview

Code

BT-MCA2701

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TNFRSF11A (AA: extra 30-212) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Uniprot accession

Q9Y6Q6:;

Molecular weight

66kDa

Gene ID

8792

Synonyms

FEO;OFE;ODFR;OSTS;PDB2;RANK;CD265;OPTB7;TRANCER;LOH18CR1;TRANCE-R

Research area

Signal transduction,Cardiovascular,Immunology

Target protein

TNFRSF11A

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using TNFRSF11A mAb against human TNFRSF11A (AA: extra 30-212) recombinant protein. (Expected MW is 46 kDa)

Western blot analysis using TNFRSF11A mAb against HEK293-6e (1) and TNFRSF11A (AA: extra 30-212)-hIgGFc transfected HEK293-6e (2) cell lysate.

Western blot analysis using TNFRSF11A mouse mAb against Mouse kindey (1) and Rat kindey (2) cell lysate.

Flow cytometric analysis of HL-60 cells using TNFRSF11A mouse mAb (green) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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