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Home > Product > Antibody > TSG101 Monoclonal Antibody

TSG101 Monoclonal Antibody

TSG101 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: FCM

Product overview

Code

BT-MCA2048

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TSG101 (AA: 167-374) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Uniprot accession

Molecular weight

44kDa

Gene ID

7251

Synonyms

TSG10;VPS23

Research area

Cell Biology

Target protein

TSG101

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
FCM 1:200 - 1:400
ELISA 1:10000

Images

Western blot analysis using TSG101 mAb against human TSG101 (AA: 167-374) recombinant protein. (Expected MW is 26.3 kDa)
Western blot analysis using TSG101 mAb against HEK293-6e (1) and human TSG101 (AA: 167-374)-hIgGFc transfected HEK293-6e (2) cell lysate.
Flow cytometric analysis of THP-1 cells using TSG101 mouse mAb (green) and negative control (red).

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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