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Home > Product > Antibody > CD126 Monoclonal Antibody

CD126 Monoclonal Antibody

CD126 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,FCM

Product overview

Code

BT-MCA3040

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD126 (AA:EXTRA 20-177) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]

Uniprot accession

Molecular weight

52kDa

Gene ID

3570

Synonyms

IL6Q;gp80;CD126;HIES5;IL-6R;IL6RA;IL6RQ;IL-1Ra;IL-6RA;IL6QTL;IL-6R-1

Research area

Others

Target protein

CD126

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
FCM 1:200 - 1:400
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using CD126 mAb against human CD126 (AA:20-177) recombinant protein. (Expected MW is 20.3 kDa)
Western blot analysis using CD126 mAb against HEK293 (1) and CD126 (AA:20-177)-hIgGFc transfected HEK293-6e (2) cell lysate.
Western blot analysis using CD126 mouse mAb against Jurkat (1), MOLT4 (2),Raw264.7 (3) and THP-1 (4) cell lysate.
Flow cytometric analysis of Jurkat cells using CD126 mouse mAb (green) and negative control (red).
Flow cytometric analysis of K562 cells using CD126 mouse mAb (green) and negative control (red).
Flow cytometric analysis of THP-1 cells using CD126 mouse mAb (green) and negative control (red).
Flow cytometric analysis of U937 cells using CD126 mouse mAb (green) and negative control (red).

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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