CD126 Monoclonal Antibody

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Home > Product > Antibody > CD126 Monoclonal Antibody

CD126 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,IHC,ICC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,IHC,ICC,FCM

Product overview

Code

BT-MCA2031

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD126 (AA: EXTRA 20-177) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]

Uniprot accession

P08887:;

Molecular weight

52kDa

Gene ID

3570

Synonyms

IL6Q;gp80;CD126;HIES5;IL-6R;IL6RA;IL6RQ;IL-1Ra;IL-6RA;IL6QTL;IL-6R-1

Research area

Others

Target protein

CD126

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
ICC	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using CD126 mAb against human CD126 (AA:20-177) recombinant protein. (Expected MW is 20.3 kDa)

Western blot analysis using CD126 mAb against HEK293 (1) and CD126 (AA:20-177)-hIgGFc transfected HEK293-6e (2) cell lysate.

Western blot analysis using CD126 mouse mAb against Jurkat (1), MOLT4 (2), Raw264.7 (3)and THP-1 (4) cell lysate.

Immunofluorescence analysis of Hela cells using CD126 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Jurkat cells using CD126 mouse mAb (green) and negative control (red).

Flow cytometric analysis of K562 cells using CD126 mouse mAb (green) and negative control (red).

Flow cytometric analysis of THP-1 cells using CD126 mouse mAb (green) and negative control (red).

Flow cytometric analysis of U937 cells using CD126 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using CD126 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using CD126 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

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