XRCC1 Monoclonal Antibody

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Home > Product > Antibody > XRCC1 Monoclonal Antibody

XRCC1 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA4201

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human XRCC1 (AA: 1-150) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Uniprot accession

P18887:;

Molecular weight

69.5kDa

Gene ID

7515

Synonyms

RCC;SCAR26

Research area

Epigenetics and Nuclear Signaling

Target protein

XRCC1

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using XRCC1 mAb against human XRCC1 (AA: 1-150) recombinant protein. (Expected MW is 42.5 kDa)

Western blot analysis using XRCC1 mAb against HEK293-6e (1) and human XRCC1-hIgGFc transfected HEK293-6e (2) cell lysate.

Flow cytometric analysis of A375 cells using XRCC1 mouse mAb (green) and negative control (red).

Flow cytometric analysis of Jurkat cells using XRCC1 mouse mAb (green) and negative control (red).

Flow cytometric analysis of K562 cells using XRCC1 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using XRCC1 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using XRCC1 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using XRCC1 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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