GZMK Monoclonal Antibody

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Home > Product > Antibody > GZMK Monoclonal Antibody

GZMK Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: IHC,FCM

Product overview

Code

BT-MCA4649

Host

Mouse

Isotype

Mouse IgG2b

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human GZMK (AA: 27-264) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

Uniprot accession

P49863:;

Molecular weight

29kDa

Gene ID

3003

Synonyms

TRYP2

Research area

Cell Biology

Target protein

GZMK

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using GZMK mAb against human GZMK (AA: 27-264) recombinant protein. (Expected MW is 28.7kDa)

Western blot analysis using GZMK mAb against HEK293-6e (1) and GZMK (AA: 27-264)-hIgGFc transfected HEK293-6e (2) cell lysate.

Flow cytometric analysis of Jurkat cells using GZMK mouse mAb (green) and negative control (red).

Flow cytometric analysis of MOLT4 cells using GZMK mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded tonsil tissues using GZMK mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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