PRF1 Monoclonal Antibody

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Home > Product > Antibody > PRF1 Monoclonal Antibody

PRF1 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA3950

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human PRF1 (AA: extra 148-372) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood.

Uniprot accession

P14222:;

Molecular weight

61.3kDa

Gene ID

5551

Synonyms

P1;PFP;HPLH2

Research area

Others

Target protein

PRF1

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using PRF1 mAb against human PRF1 (AA: extra 148-372) recombinant protein. (Expected MW is 29.7 kDa)

Western blot analysis using PRF1 mAb against HEK293-6e (1) and PRF1 (AA: extra 148-372)-hIgGFc transfected HEK293-6e (2) cell lysate.

Western blot analysis using PRF1 mouse mAb against mouse liver (1) cell lysate.

Flow cytometric analysis of Jurkat cells using PRF1 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using PRF1 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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