CD105 Monoclonal Antibody

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Home > Product > Antibody > CD105 Monoclonal Antibody

CD105 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA3999

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD105 (AA: extra 342-586) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

P17813:;

Molecular weight

70.6kDa

Gene ID

2022

Synonyms

ENG;END;HHT1;ORW1

Research area

Others

Target protein

CD105

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using CD105 mAb against human CD105 (AA: extra 342-586) recombinant protein. (Expected MW is 42.8 kDa)

Western blot analysis using CD105 mAb against HEK293-6e (1) and CD105 (AA: extra 342-586)-hIgGFc transfected HEK293-6e (2) cell lysate.

Western blot analysis using CD105 mouse mAb against HUVEC (1), HUVE-12 (2), SH-SY5Y (3), and HEK293 (4) cell lysate.

Flow cytometric analysis of THP-1 cells using CD105 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD105 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using CD105 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

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