C-MYC Monoclonal Antibody

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Home > Product > Antibody > C-MYC Monoclonal Antibody

C-MYC Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: IHC,FCM

Product overview

Code

BT-MCA2321

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human C-MYC (AA: (290-439)) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Uniprot accession

P01106:;

Molecular weight

32.1|57|48.8kDa

Gene ID

4609

Synonyms

MRTL;MYCC;c-Myc;bHLHe39

Research area

Others

Target protein

C-MYC

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200-1:1000
FCM	1:200-1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

Western blot analysis using C-MYC mAb against human C-MYC (AA: (290-439)) recombinant protein.

Western blot analysis using C-MYC mAb against HEK293-6e (1) and C-MYC (AA: (290-439))-hIgGFc transfected HEK293-6e (2) cell lysate.

Flow cytometric analysis of Hela cells using C-MYC mouse mAb (green) and negative control (red).

Flow cytometric analysis of Hepg2 cells using C-MYC mouse mAb (green) and negative control (red).

Flow cytometric analysis of Lovo cells using C-MYC mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using C-MYC mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using C-MYC mouse mAb with DAB staining.

Protocols

> Protocol Booklet

Customer reviews and Q&As

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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