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Home > Product > Antibody > NEFH Monoclonal Antibody

NEFH Monoclonal Antibody

NEFH Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: IHC

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: IHC

Product overview

Code

BT-MCA2337

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human NEFH (AA: 2-251) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Uniprot accession

Molecular weight

112.4kDa

Gene ID

4744

Synonyms

NFH;CMT2CC

Research area

Neuroscience

Target protein

NEFH

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
IHC-p 1:200-1:1000
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
Western blot analysis using NEFH mAb against human NEFH (AA: 2-251) recombinant protein. (Expected MW is 29.6 kDa)
Western blot analysis using NEFH mAb against HEK293-6e (1) and NEFH (AA: 2-251)-hIgGFc transfected HEK293-6e (2) cell lysate.
Immunohistochemical analysis of paraffin-embedded human cerebrum tissues using NEFH mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human cerebellum tissues using NEFH mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using NEFH mouse mAb with DAB staining.

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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