ZAP70 Monoclonal Antibody

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Home > Product > Antibody > ZAP70 Monoclonal Antibody

ZAP70 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB

Product overview

Code

BT-MCA2248

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human ZAP70 (AA: 169-390) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Uniprot accession

P43403:;

Molecular weight

69.9kDa

Gene ID

7535

Synonyms

SRK;STD;TZK;STCD;IMD48;ADMIO2;ZAP-70

Research area

Immunology

Target protein

ZAP70

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using ZAP70 mAb against human ZAP70 (AA: 169-390) recombinant protein. (Expected MW is 27.9 kDa)

Western blot analysis using ZAP70 mAb against HEK293 (1) and ZAP70 (AA: 169-390)-hIgGFc transfected HEK293 (2) cell lysate.

Western blot analysis using ZAP70 mouse mAb against MOLT4 (1) cell lysate.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

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