GPC3 Monoclonal Antibody

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Home > Product > Antibody > GPC3 Monoclonal Antibody

GPC3 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: FCM

Product overview

Code

BT-MCA2347

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human GPC3 (AA: 359-554) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Uniprot accession

P51654:;

Molecular weight

65.5kDa

Gene ID

2719

Synonyms

SGB;DGSX;MXR7;SDYS;SGBS;OCI-5;SGBS1;GTR2-2

Research area

Stem Cells

Target protein

GPC3

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using GPC3 mAb against human GPC3 (AA: 359-554) recombinant protein. (Expected MW is 25 kDa)

Western blot analysis using GPC3 mAb against HEK293 (1) and GPC3 (AA: 359-554)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric analysis of SK-N-SH cells using GPC3 mouse mAb (green) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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