ZAP70 Monoclonal Antibody

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Home > Product > Antibody > ZAP70 Monoclonal Antibody

ZAP70 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: WB,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: WB,FCM

Product overview

Code

BT-MCA3869

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human ZAP70 (AA: 169-390) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Uniprot accession

P43403:;

Molecular weight

69.9kDa

Gene ID

7535

Synonyms

SRK;STD;TZK;STCD;IMD48;ADMIO2;ZAP-70

Research area

Immunology

Target protein

ZAP70

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using ZAP70 mAb against human ZAP70 (AA: 169-390) recombinant protein. (Expected MW is 27.9 kDa)

Western blot analysis using ZAP70 mAb against HEK293 (1) and ZAP70 (AA: 169-390)-hIgGFc transfected HEK293 (2) cell lysate.

Western blot analysis using ZAP70 mouse mAb against MLOT4 (1) cell lysate.

Flow cytometric analysis of Jurkat cells using ZAP70 mouse mAb (green) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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