TIA1 Monoclonal Antibody

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Blood coagulation
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Home > Product > Antibody > TIA1 Monoclonal Antibody

TIA1 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Others

Applications: IHC,ICC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Others

Applications: IHC,ICC,FCM

Product overview

Code

BT-MCA2012

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TIA1 (AA: 1-215) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene.

Uniprot accession

P31483:;

Molecular weight

43kDa

Gene ID

7072

Synonyms

WDM;TIA-1

Research area

Epigenetics and nuclear signaling,Cancer,Cell biology,Immunology

Target protein

TIA1

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200-1:1000
ICC	1:200 - 1:1000
FCM	1:200-1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

Western blot analysis using TIA1 mAb against human TIA1 (AA: 1-215) recombinant protein. (Expected MW is 26.8 kDa)

Western blot analysis using TIA1 mAb against HEK293 (1) and TIA1 (AA: 1-215)-hIgGFc transfected HEK293 (2) cell lysate.

Immunofluorescence analysis of Hela cells using TIA1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using TIA1 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using TIA1 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

Customer reviews and Q&As

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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