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Home > Product > Antibody > KAT6B Monoclonal Antibody

KAT6B Monoclonal Antibody

KAT6B Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: Others

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: Others

Product overview

Code

BT-MCA2375

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

Uniprot accession

Molecular weight

231.4kDa

Gene ID

23522

Synonyms

qkf;MORF;MOZ2;GTPTS;MYST4;ZC2HC6B;querkopf

Research area

Epigenetics and nuclear signaling

Target protein

KAT6B

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using KAT6B mAb against human KAT6B (AA: 1186-1318) recombinant protein. (Expected MW is 41.3 kDa)
Western blot analysis using KAT6B mAb against HEK293 (1) and KAT6B (AA: 1186-1318)-hIgGFc transfected HEK293 (2) cell lysate.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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