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Home > Product > Antibody > PIDD1 Monoclonal Antibody

PIDD1 Monoclonal Antibody

PIDD1 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: Others

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: Others

Product overview

Code

BT-MCA4604

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Uniprot accession

Molecular weight

99.7kDa

Gene ID

55367

Synonyms

LRDD;PIDD

Research area

Others

Target protein

PIDD1

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using PIDD1 mAb against human PIDD1 (AA: 776-910) recombinant protein. (Expected MW is 40.8 kDa)
Western blot analysis using PIDD1 mAb against HEK293 (1) and PIDD1 (AA: 776-910)-hIgGFc transfected HEK293 (2) cell lysate.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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