CD27 Monoclonal Antibody

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Blood coagulation
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Home > Product > Antibody > CD27 Monoclonal Antibody

CD27 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: FCM

Product overview

Code

BT-MCA4261

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD27 (AA: extra 20-144) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Uniprot accession

P26842:;

Molecular weight

29.1kDa

Gene ID

939

Synonyms

T14;S152;Tp55;TNFRSF7;S152. LPFS2

Research area

Cancer,Immunology,Stem cells

Target protein

CD27

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using CD27 mAb against human CD27 (AA: extra 20-144) recombinant protein. (Expected MW is 39.8 kDa)

Western blot analysis using CD27 mAb against HEK293 (1) and CD27 (AA: extra 20-144)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric analysis of HL-60 cells using CD27 mouse mAb (green) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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