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Home > Product > Antibody > CD369 Monoclonal Antibody

CD369 Monoclonal Antibody

CD369 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: ICC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: ICC,FCM

Product overview

Code

BT-MCA2688

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD369 (AA: extra 66-247) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Uniprot accession

Molecular weight

27.6kDa

Gene ID

64581

Synonyms

CLEC7A;BGR;CANDF4;SCARE2;DECTIN1;CLECSF12

Research area

Others

Target protein

CD369

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
ICC 1:200 - 1:1000
FCM 1:200 - 1:400
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using CD369 mAb against human CD369 (AA: extra 66-247) recombinant protein. (Expected MW is 46.5 kDa)
Western blot analysis using CD369 mAb against HEK293 (1) and CD369 (AA: extra 66-247)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric analysis of HL-60 cells using CD369 mouse mAb (green) and negative control (red).
Immunofluorescence analysis of Hela cells using CD369 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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