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Home > Product > Antibody > CD239 Monoclonal Antibody

CD239 Monoclonal Antibody

CD239 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: IHC,FCM

Product overview

Code

BT-MCA4466

Host

Mouse

Isotype

Mouse IgG2a

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD239 (AA: extra 32-197) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

67.4kDa

Gene ID

67.4kDa

Synonyms

BCAM;AU;LU;MSK19

Research area

Others

Target protein

CD239

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
IHC-p 1:200 - 1:1000
FCM 1:200 - 1:400
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using CD239 mAb against human CD239 (AA: extra 32-197) recombinant protein. (Expected MW is 44.1 kDa)
Western blot analysis using CD239 mAb against HEK293 (1) and CD239 (AA: extra 32-197)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric analysis of MOLT4 cells using CD239 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CD239 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using CD239 mouse mAb with DAB staining.

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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