CD222 Monoclonal Antibody

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Home > Product > Antibody > CD222 Monoclonal Antibody

CD222 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: FCM

Product overview

Code

BT-MCA4667

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

Uniprot accession

P11717:;

Molecular weight

274kDa

Gene ID

3482

Synonyms

IGF2R;MPR1;MPRI;CIMPR;M6P-R;MPR300;CI-M6PR;MPR 300;M6P/IGF2R

Research area

Others

Target protein

CD222

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using CD222 mAb against human CD222 (AA: 160-311) recombinant protein. (Expected MW is 42.9 kDa)

Western blot analysis using CD222 mAb against HEK293 (1) and CD222 (AA: 160-311)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric analysis of HL-60 cells using CD222 mouse mAb (green) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

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