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Home > Product > Antibody > TNFRSF10B Monoclonal Antibody

TNFRSF10B Monoclonal Antibody

TNFRSF10B Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: Others

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: Others

Product overview

Code

BT-MCA4707

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TNFRSF10B (AA: extra 56-210) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Uniprot accession

Molecular weight

47.9kDa

Gene ID

8795

Synonyms

DR5;CD262;KILLER;TRICK2;TRICKB;ZTNFR9;TRAILR2;TRICK2A;TRICK2B;TRAIL-R2;KILLER/DR5

Research area

Signal transduction,Cardiovascular,Cancer

Target protein

TNFRSF10B

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using TNFRSF10B mAb against human TNFRSF10B (AA: extra 56-210) recombinant protein. (Expected MW is 43 kDa)
Western blot analysis using TNFRSF10B mAb against HEK293 (1) and TNFRSF10B (AA: extra 56-210)-hIgGFc transfected HEK293 (2) cell lysate.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

Add to Cart

Lead time: Within one week

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