CD170 Monoclonal Antibody

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Home > Product > Antibody > CD170 Monoclonal Antibody

CD170 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: FCM

Product overview

Code

BT-MCA4028

Host

Mouse

Isotype

Mouse IgG2a

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Uniprot accession

O15389:;

Molecular weight

60.7kDa

Gene ID

8778

Synonyms

SIGLEC5;OBBP2;CD33L2;OB-BP2;SIGLEC-5

Research area

Others

Target protein

CD170

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using CD170 mAb against human CD170 (AA: extra 17-230) recombinant protein. (Expected MW is 50.3 kDa)

Western blot analysis using CD170 mAb against HEK293 (1) and CD170 (AA: extra 17-230)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric analysis of HL-60 cells using CD170 mouse mAb (green) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

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