CD11a Monoclonal Antibody

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Home > Product > Antibody > CD11a Monoclonal Antibody

CD11a Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB,IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB,IHC,FCM

Product overview

Code

BT-MCA4341

Host

Mouse

Isotype

Mouse IgG2a

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD11a (AA: extra 26-194) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

P20701:;

Molecular weight

128.8kDa

Gene ID

3683

Synonyms

ITGAL;LFA-1;LFA1A

Research area

Others

Target protein

CD11a

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using CD11a mAb against human CD11a (AA: extra 26-194) recombinant protein. (Expected MW is 44.4 kDa)

Western blot analysis using CD11a mAb against HEK293 (1) and CD11a (AA: extra 26-194)-hIgGFc transfected HEK293 (2) cell lysate.

Western blot analysis using CD11a mouse mAb against HL-60 (1), A549 (2), and SW620 (3) cell lysate.

Flow cytometric analysis of HL-60 cells using CD11a mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded tonsil tissues using CD11a mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD11a mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

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