TNFRSF18 Monoclonal Antibody

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Blood coagulation
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Home > Product > Antibody > TNFRSF18 Monoclonal Antibody

TNFRSF18 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: IHC,FCM

Product overview

Code

BT-MCA2323

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TNFRSF18 (AA: extra 26-162) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Uniprot accession

Q9Y5U5:;

Molecular weight

26kDa

Gene ID

8784

Synonyms

AITR;GITR;CD357;GITR-D

Research area

Immunology,Cell biology,Signal transduction

Target protein

TNFRSF18

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using TNFRSF18 mAb against human TNFRSF18 (AA: extra 26-162) recombinant protein. (Expected MW is 40.6 kDa)

Western blot analysis using TNFRSF18 mAb against HEK293 (1) and TNFRSF18 (AA: extra 26-162)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric analysis of Jurkat cells using TNFRSF18 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using TNFRSF18 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded colon cancer tissues using TNFRSF18 mouse mAb with DAB staining.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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