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Home > Product > Antibody > TIM3 Monoclonal Antibody

TIM3 Monoclonal Antibody

TIM3 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: FCM

Product overview

Code

BT-MCA3591

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TIM3 (AA: 224-301) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Uniprot accession

Molecular weight

33.4kDa

Gene ID

84868

Synonyms

HAVCR2;CD366;KIM-3;TIMD3;Tim-3;TIMD-3;HAVcr-2

Research area

Others

Target protein

TIM3

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
FCM 1:200 - 1:400
ELISA 1:10000

Images

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using TIM3 mAb against human TIM3 (AA: 224-301) recombinant protein. (Expected MW is 34.9 kDa)
Western blot analysis using TIM3 mAb against HEK293 (1) and TIM3 (AA: 224-301)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric analysis of HL-60 cells using TIM3 mouse mAb (green) and negative control (red).

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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