MDM2 Monoclonal Antibody

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Home > Product > Antibody > MDM2 Monoclonal Antibody

MDM2 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: FCM

Product overview

Code

BT-MCA2537

Host

Mouse

Isotype

Mouse IgG2a

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Synthesized peptide of human MDM2 (AA: ASEQETLVRPKPLLc).

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Uniprot accession

Q00987:;

Molecular weight

55.2kDa

Gene ID

4193

Synonyms

DMX;hdm2;ACTFS

Research area

Cell Biology

Target protein

MDM2

Recommended dilution

Application	Dilution
FCM	1:200 - 1:400
ELISA	1:10000

Images

Flow cytometric analysis of Hela cells using MDM2 mouse mAb (green) and negative control (red).

Flow cytometric analysis of Jurkat cells using MDM2 mouse mAb (green) and negative control (red).

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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