BT-MCA3077

Mouse

Mouse IgG1

100μL,50μL

Monoclonal

Purified recombinant fragment of human PRKACA (AA: 1-120) expressed in E. Coli.

Purified antibody in PBS with 0.05% sodium azide.

Store at 4°C short term. Aliquot and store at -20°C long term.

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

P17612:;

40.6kDa

5566

PKACA

Others

PRKACA