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Home > Product > Antibody > Artemis Polyclonal Antibody

Artemis Polyclonal Antibody

Artemis Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: IHC-p, IF, ELISA

Product overview

Full product name

Artemis Antibody

Code

BT-AP00637

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Artemis. AA range:482-531

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

DCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.

Uniprot accession

Molecular weight

78436

Gene ID

Human: 64421

Synonyms

DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein

Research area

Epigenetics and Nuclear Signaling

Target protein

DCLRE1C

Recommended dilution

Application Dilution
IHC 1: 100 - 1: 300
IF 1: 200 - 1: 1000
ELISA 1: 10000

Images

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Artemis Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of NIH/3T3 cells, using Artemis Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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