Atm Polyclonal Antibody

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Blood coagulation
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Home > Product > Antibody > Atm Polyclonal Antibody

Atm Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-p, ELISA

Product overview

Full product name

Atm Antibody

Code

BT-AP00725

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human ATM. AA range:1950-1999

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The protein encoded by ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Uniprot accession

Human:;Mouse:;

Molecular weight

350644

Gene ID

Human: 472; Mouse: 11920

Synonyms

ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated

Research area

Epigenetics and Nuclear Signaling

Target protein

ATM

Recommended dilution

Application	Dilution
IHC	1: 100 - 1: 300
ELISA	1: 40000

Images

Western Blot analysis of MOUSE-BRAIN K562 cells using Atm Polyclonal Antibody diluted at 1:500

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ATM Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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