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Home > Product > Antibody > Caspase-14 Polyclonal Antibody

Caspase-14 Polyclonal Antibody

Caspase-14 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Caspase-14 Antibody

Code

BT-AP01197

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from Caspase-14 . at AA range: 110-190

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

CASP14 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 14 has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of caspase 14 may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Uniprot accession

Molecular weight

27680

Gene ID

Human: 23581

Synonyms

CASP14; Caspase-14; CASP-14

Research area

Cell Biology

Target protein

CASP14

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 40000

Images

Western Blot analysis of various cells using Caspase-14 Polyclonal Antibody

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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