Catenin-Beta1 Polyclonal Antibody

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Home > Product > Antibody > Catenin-Beta1 Polyclonal Antibody

Catenin-Beta1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Catenin-beta1 Antibody

Code

BT-AP01233

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Catenin-beta1. AA range:626-675

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The protein (catenin beta 1) encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

85497

Gene ID

Human: 1499; Mouse: 12387; Rat: 84353

Synonyms

CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin

Research area

Signal Transduction

Target protein

CTNNB1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
IF	1: 200 - 1: 1000
ELISA	1: 10000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Catenin-beta1 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HeLa cells, using Catenin-beta1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of HeLa cells using Catenin-β1 Polyclonal Antibody diluted at 1:1000

Western Blot analysis of various cells using Catenin-β1 Polyclonal Antibody diluted at 1:1000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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