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Home > Product > Antibody > CD276 Polyclonal Antibody

CD276 Polyclonal Antibody

CD276 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product overview

Full product name

CD276 Antibody

Code

BT-AP01439

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CD276. AA range:271-320

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

CD276 antigen encoded by CD276 belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

57235

Gene ID

Human: 80381; Mouse: 102657; Rat: 315716

Synonyms

CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276

Research area

Immunology

Target protein

CD276

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 100 - 300
ELISA 1: 20000

Images

Immunohistochemical analysis of paraffin-embedded mouse-liver, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
Western blot analysis of lysate from 293 cells, using CD276 Antibody.
Western Blot analysis of 293 cells using CD276 Polyclonal Antibody. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded mouse-liver, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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