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Home > Product > Antibody > Claudin-4 Polyclonal Antibody

Claudin-4 Polyclonal Antibody

Claudin-4 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-p, ELISA

Product overview

Full product name

Claudin-4 Antibody

Code

BT-AP01846

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Claudin 4. AA range:160-209

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Claudin 4 encoded by this intronless gene (CLDN4) belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Uniprot accession

Molecular weight

22077

Gene ID

Human: 1364; Mouse: 12740

Synonyms

CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein

Research area

Signal Transduction

Target protein

CLDN4

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC 1: 100 - 1: 300
ELISA 1: 5000

Images

Western Blot analysis of HeLa cells using Claudin-4 Polyclonal Antibody diluted at 1:2000
Western Blot analysis of various cells using Claudin-4 Polyclonal Antibody diluted at 1:2000
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Claudin 4 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HeLa cells, using Claudin 4 Antibody. The lane on the right is blocked with the synthesized peptide.
Western Blot analysis of mouse-BRAIN cells using Claudin-4 Polyclonal Antibody diluted at 1:500
Western blot analysis of lysates from COLO cells, using Claudin 4 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Claudin 4 Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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