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Home > Product > Antibody > Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody

Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody

Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

Cleaved-Caspase-2 p18 (G170) Antibody

Code

BT-AP01886

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 2. AA range:151-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

CASP2 encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. Caspase 2 may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Uniprot accession

Molecular weight

50685

Gene ID

Human: 835

Synonyms

CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1

Research area

Cell Biology

Target protein

CASP2

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 40000

Images

Western Blot analysis of Jurkat cells using Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody diluted at 1:2000
Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using Caspase 2 (p18,Cleaved-Gly170) Antibody. The lane on the right is blocked with the synthesized peptide.
Western Blot analysis of various cells using Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody diluted at 1:2000

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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