Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody

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Home > Product > Antibody > Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody

Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

Cleaved-Caspase-2 p18 (G170) Antibody

Code

BT-AP01886

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 2. AA range:151-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

CASP2 encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. Caspase 2 may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Uniprot accession

Human:;Mouse:;

Molecular weight

50685

Gene ID

Human: 835

Synonyms

CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1

Research area

Cell Biology

Target protein

CASP2

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 40000

Images

Western Blot analysis of Jurkat cells using Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody diluted at 1:2000

Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using Caspase 2 (p18,Cleaved-Gly170) Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody diluted at 1:2000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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