Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody

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Home > Product > Antibody > Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody

Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC-p, ELISA

Product overview

Full product name

Cleaved-Caspase-6 p18 (D179) Antibody

Code

BT-AP01898

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

CASP6 encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme.Caspase 6 is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

33310

Gene ID

Human: 839

Synonyms

CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Research area

Neuroscience

Target protein

CASP6

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
ELISA	1: 40000

Images

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 6 (Cleaved-Asp162) Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from 293 cells, treated with Etoposide 25uM 60', using Caspase 6 (Cleaved-Asp162) Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody diluted at 1:1000

Western Blot analysis of 293 cells using Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody diluted at 1:1000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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