Cleaved-Integrin Alpha6 LC (E942) Polyclonal Antibody

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Home > Product > Antibody > Cleaved-Integrin Alpha6 LC (E942) Polyclonal Antibody

Cleaved-Integrin Alpha6 LC (E942) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Cleaved-Integrin alpha6 LC (E942) Antibody

Code

BT-AP01931

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human ITGA6. AA range:923-972

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

ITGA6 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;

Molecular weight

126619

Gene ID

Human: 3655

Synonyms

ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD antigen CD49f

Research area

Signal Transduction

Target protein

ITGA6

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 10000

Images

Western Blot analysis of various cells using Cleaved-Integrin α6 LC (E942) Polyclonal Antibody

Western blot analysis of lysates from HeLa cells, treated with etoposide 25uM 24h, using ITGA6 (light chain,Cleaved-Glu942) Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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