Cleaved-MMP-12 (G106) Polyclonal Antibody

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Home > Product > Antibody > Cleaved-MMP-12 (G106) Polyclonal Antibody

Cleaved-MMP-12 (G106) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Cleaved-MMP-12 (G106) Antibody

Code

BT-AP01945

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human MMP12. AA range:87-136

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

MMP12 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Matrix metallopeptidase 12 degrades soluble and insoluble elastin. MMP12 may play a role in aneurysm formation and mutations MMP12 are associated with lung function and chronic obstructive pulmonary disease (COPD). MMP12 is part of a cluster of MMP genes on chromosome 11.

Uniprot accession

Human:;Mouse:;

Molecular weight

54002

Gene ID

Human: 4321

Synonyms

MMP12; HME; Macrophage metalloelastase; MME; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12

Research area

Cardiovascular

Target protein

MMP12

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 20000

Images

Western Blot analysis of various cells using Cleaved-MMP-12 (G106) Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from NIH/3T3 cells, treated with etoposide 25uM 1h, using MMP12 (Cleaved-Glu106) Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of VEC cells using Cleaved-MMP-12 (G106) Polyclonal Antibody diluted at 1:1000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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