Cleaved-Spectrin Alpha II (D1185) Polyclonal Antibody

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Home > Product > Antibody > Cleaved-Spectrin Alpha II (D1185) Polyclonal Antibody

Cleaved-Spectrin Alpha II (D1185) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Cleaved-Spectrin alpha II (D1185) Antibody

Code

BT-AP01963

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human SPTA2. AA range:1136-1185

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. Spectrin alpha chain non-erythrocytic 1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in SPTAN1 are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;

Molecular weight

284539

Gene ID

Human: 6709

Synonyms

SPTAN1; NEAS; SPTA2; Spectrin alpha chain; non-erythrocytic 1; Alpha-II spectrin; Fodrin alpha chain; Spectrin, non-erythroid alpha subunit

Research area

Signal Transduction

Target protein

SPTAN1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 10000

Images

Western Blot analysis of various cells using Cleaved-Spectrin α II (D1185) Polyclonal Antibody diluted at 1:500

Western Blot analysis of customer's (cat sample) using Cleaved-Spectrin α II (D1185) Polyclonal Antibody diluted at 1:500

Western blot analysis of lysates from HeLa and A549 cells, treated with etoposide 25uM 24H, using SPTA2 (Cleaved-Asp1185) Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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