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Home > Product > Antibody > CYP11A1 Polyclonal Antibody

CYP11A1 Polyclonal Antibody

CYP11A1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-p, ELISA

Product overview

Full product name

CYP11A1 Antibody

Code

BT-AP02375

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human CYP11A1. AA range:411-460

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

CYP11A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Cholesterol side-chain cleavage enzyme mitochondrial localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

Uniprot accession

Molecular weight

60102

Gene ID

Human: 1583

Synonyms

CYP11A1; CYP11A; Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)

Research area

Cardiovascular

Target protein

CYP11A1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 100 - 300
ELISA 1: 20000

Images

Western blot analysis of lysate from K562 cells, using CYP11A1 Antibody.
Western Blot analysis of K562 cells using CYP11A1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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