D4DR Polyclonal Antibody

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Home > Product > Antibody > D4DR Polyclonal Antibody

D4DR Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF, ELISA

Product overview

Full product name

D4DR Antibody

Code

BT-AP02487

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

DRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in DRD4 have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

48361

Gene ID

Human: 1815; Mouse: 13491; Rat: 25432

Synonyms

DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor

Research area

Neuroscience

Target protein

DRD4

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IF	1: 200 - 1: 1000
ELISA	1: 40000

Images

Western Blot analysis of K562 cells using D4DR Polyclonal Antibody

Western blot analysis of lysates from MCF-7 and HUVEC cells, using DRD4 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from RAW264.7cells using DRD4 antibody.

Immunofluorescence analysis of MCF7 cells, using DRD4 Antibody. The picture on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using D4DR Polyclonal Antibody

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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