DNA Ligase I Polyclonal Antibody

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Home > Product > Antibody > DNA Ligase I Polyclonal Antibody

DNA Ligase I Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-p, ELISA

Product overview

Full product name

DNA Ligase I Antibody

Code

BT-AP02651

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human DNL1. AA range:111-160

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

LIG1 encodes a member of the ATP-dependent DNA ligase protein family. DNA ligase 1 functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of LIG1 may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;

Molecular weight

101736

Gene ID

Human: 3978

Synonyms

LIG1; DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1

Research area

Epigenetics and Nuclear Signaling

Target protein

LIG1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
ELISA	1: 20000

Images

Western Blot analysis of various cells using DNA Ligase I Polyclonal Antibody diluted at 1:2000 cells nucleus.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DNL1 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HT-29 cells, using DNL1 Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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