Product overview
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Background
DVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
Uniprot accession
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Recommended dilution
| Application | Dilution |
|---|---|
| WB | 1: 500 - 1: 2000 |
| IHC | 1: 100 - 1: 300 |
| ELISA | 1: 40000 |
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